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rdf:type
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http://linked.open...gbank/description
| - Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia. Regular use leads to tolerance, and it is usually not effective for more than 7 days. Structurally, it does not resemble the barbituates, but it shares many effects with this class of drugs; the depressant effects of ethinamate are, however, generally milder than those of most barbiturates. (en)
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http://linked.open...gy/drugbank/group
| - approved (en)
- illicit (en)
- withdrawn (en)
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http://linked.open...drugbank/halfLife
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http://linked.open...ugbank/indication
| - Used for the short-term treatment of insomnia, however, it generally has been replaced by other sedative-hypnotic agents. (en)
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sameAs
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Title
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adms:identifier
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http://linked.open...mechanismOfAction
| - The mechanism of action is not known. However, studies have shown that ethinamate inhibits carbonic anhydrases I and II (J Biol Chem. 1992 Dec 15;267(35):25044-50). This inhibition by ethinamate is not sufficiently strong, however, to implicate carbonic anhydrases I and II in the mechanism of action. (en)
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http://linked.open.../drugbank/synonym
| - Ethinamate (en)
- 1-Ethynylcyclohexanol carbamate (en)
- Aethinyl-cyclohexyl-carbamat (en)
- Ethinamatum (en)
- Etinamato (en)
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http://linked.open...drugbank/toxicity
| - Symptoms of overdose include shortness of breath or slow or troubled breathing, slow heartbeat, severe weakness, chronic confusion, slurred speech, and staggering. (en)
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http://linked.open...ynthesisReference
| - Junkmann, K. and Pfeiffer, H.; US. Patent 2,816,910; December 17, 1957; assigned to Schering AG, Germany. (en)
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http://linked.open...y/mesh/hasConcept
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http://linked.open...ugbank/IUPAC-Name
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http://linked.open...gy/drugbank/InChI
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http://linked.open...Molecular-Formula
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http://linked.open.../Molecular-Weight
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http://linked.open...noisotopic-Weight
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http://linked.open...y/drugbank/SMILES
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http://linked.open.../Water-Solubility
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http://linked.open...ogy/drugbank/logP
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http://linked.open...ogy/drugbank/logS
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http://linked.open...nd-Acceptor-Count
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http://linked.open...-Bond-Donor-Count
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http://linked.open...drugbank/InChIKey
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http://linked.open...urface-Area--PSA-
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http://linked.open...nk/Polarizability
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http://linked.open...bank/Refractivity
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http://linked.open...atable-Bond-Count
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http://linked.open...ugbank/absorption
| - Rapidly absorbed following oral administration. (en)
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http://linked.open.../affectedOrganism
| - Humans and other mammals (en)
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http://linked.open...casRegistryNumber
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http://linked.open...k/Bioavailability
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http://linked.open...ank/Boiling-Point
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http://linked.open...bank/Ghose-Filter
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http://linked.open...nk/MDDR-Like-Rule
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http://linked.open...ank/Melting-Point
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http://linked.open...k/Number-of-Rings
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http://linked.open...siological-Charge
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http://linked.open...bank/Rule-of-Five
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http://linked.open...tional-IUPAC-Name
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http://linked.open...strongest-acidic-
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