About: Pseudoephedrine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	An alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used in the treatment of several disorders including asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B4DE3-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4DE4-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4DE5-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4DE6-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4DE7-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4DE8-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4DE9-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	9-16 hours (en)
http://linked.open...ugbank/indication	For the treatment of nasal congestion, sinus congestion, Eustachian tube congestion, and vasomotor rhinitis, and as an adjunct to other agents in the optimum treatment of allergic rhinitis, croup, sinusitis, otitis media, and tracheobronchitis. Also used as first-line therapy of priapism. (en)
http://linked.open...bank/manufacturer	Pharmeral inc Eli lilly and co
sameAs	Pseudoephedrine Pseudoephedrine
Title	Pseudoephedrine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00852/identifier/chebi/51209 http://linked.opendata.cz/resource/drugbank/drug/DB00852/identifier/chemspider/6761 http://linked.opendata.cz/resource/drugbank/drug/DB00852/identifier/drugbank/DB00852 http://linked.opendata.cz/resource/drugbank/drug/DB00852/identifier/national-drug-code-directory/11822-0054-6 http://linked.opendata.cz/resource/drugbank/drug/DB00852/identifier/pubchem-compound/7028 http://linked.opendata.cz/resource/drugbank/drug/DB00852/identifier/pubchem-substance/46508190 http://linked.opendata.cz/resource/drugbank/drug/DB00852/identifier/pharmgkb/PA451170 http://linked.opendata.cz/resource/drugbank/drug/DB00852/identifier/wikipedia/Pseudoephedrine
http://linked.open...mechanismOfAction	Pseudoephedrine acts directly on both alpha- and, to a lesser degree, beta-adrenergic receptors. Through direct action on alpha-adrenergic receptors in the mucosa of the respiratory tract, pseudoephedrine produces vasoconstriction. Pseudoephedrine relaxes bronchial smooth muscle by stimulating beta2-adrenergic receptors. Like ephedrine, pseudoephedrine releasing norepinephrine from its storage sites, an indirect effect. This is its main and direct mechanism of action. The displaced noradrenaline is released into the neuronal synapse where it is free to activate the postsynaptic adrenergic receptors. (en)
http://linked.open...drugbank/packager	Alphapharm Party Ltd. Apotex Inc. Bergen Brunswig Bio Pharm Inc. Able laboratories inc Accucaps Industries Ltd. Advanced Pharmaceutical Services Inc. Ajanta Pharma Ltd. Amend Amerisource Health Services Corp. Apace Packaging Apotheca Inc. APP Pharmaceuticals A-S Medication Solutions LLC Avkare Incorporated Avpak Pfizer Inc. Pharmaceutical Utilization Management Program VA Inc. Bryant Ranch Prepack Cadista Pharmaceuticals Inc. Cardinal Health Pharmaceutical Utilization Management Program VA Inc. Chemins Co. Inc. Comprehensive Consultant Services Inc. Consolidated Midland Corp. Contract Pharm Coupler Enterprises Inc. CVS Pharmacy Cypress Pharmaceutical Inc. DAVA Pharmaceuticals Deca Pharmaceuticals LLC Dept Health Central Pharmacy Pfizer Inc. Direct Dispensing Inc. Dispensing Solutions Pharmaceutical Utilization Management Program VA Inc. Sandoz Excellium Pharmaceutical Inc. Heartland Repack Services LLC Ivax Pharmaceuticals JLM Pharmatech AAIPharma Inc. B&B Pharmaceuticals Dept Health Central Pharmacy Direct Dispensing Inc. Dispensing Solutions Diversified Healthcare Services Inc. Emcure Pharmaceuticals Ltd. Heartland Repack Services LLC Ivax Pharmaceuticals Lake Erie Medical and Surgical Supply Abc holding corp Actavis elizabeth llc Alra laboratories inc Murfreesboro Pharmaceutical Nursing Supply Barr laboratories inc Caraco pharmaceutical laboratories ltd Dava pharmaceuticals inc Elkins sinn div ah robins co inc Excellium pharmaceutical inc Heather drug co inc Heritage pharmaceuticals inc Akorn Inc. Inwood laboratories inc sub forest laboratories inc Ben venue laboratories inc CP Pharmaceuticals Ltd. Barr laboratories inc Cadista pharmaceuticals inc Pfizer Inc. Everylife Excellium pharmaceutical inc Halsey drug co inc APP Pharmaceuticals Hospira Inc.

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