About: L-Phenylalanine

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About: L-Phenylalanine Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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http://linked.open...gbank/description	An essential aromatic amino acid that is a precursor of melanin; dopamine; noradrenalin (norepinephrine), and thyroxine. [PubChem] (en)
http://linked.open...gy/drugbank/group	approved (en) nutraceutical (en)
http://linked.open...ugbank/indication	L-phenylalanine may be helpful in some with depression. It may also be useful in the treatment of vitiligo. There is some evidence that L-phenylalanine may exacerbate tardive dyskinesia in some schizophrenic patients and in some who have used neuroleptic drugs. (en)
sameAs	L-Phenylalanine L-Phenylalanine
Title	L-Phenylalanine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/chebi/17295 http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/chemspider/5910 http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/drugbank/DB00120 http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/guide-to-pharmacology/3313 http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/iuphar/3313 http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/kegg-compound/C00079 http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/kegg-drug/D00021 http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/pdb/PHE http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/pubchem-compound/6140 http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/pubchem-substance/46505708 http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/pharmgkb/PA450931 http://linked.opendata.cz/resource/drugbank/drug/DB00120/identifier/wikipedia/L-Phenylalanine
http://linked.open...mechanismOfAction	The mechanism of L-phenylalanine's putative antidepressant activity may be accounted for by its precursor role in the synthesis of the neurotransmitters norepinephrine and dopamine. Elevated brain norepinephrine and dopamine levels are thought to be associated with antidepressant effects. <br/>The mechanism of L-phenylalanine's possible antivitiligo activity is not well understood. It is thought that L-phenylalanine may stimulate the production of melanin in the affected skin (en)
http://linked.open...drugbank/packager	Magno-Humphries Laboratories
http://linked.open.../drugbank/synonym	PHENYLALANINE (en) L-Phenylalanine (en) (S)-alpha-Amino-beta-phenylpropionic acid (en) 3-phenyl-L-alanine (en) Phe (en) β-phenyl-L-alanine (en) F (en) (S)-2-Amino-3-phenylpropionic acid (en) beta-Phenyl-L-alanine (en)
http://linked.open...drugbank/toxicity	L-phenylalanine will exacerbate symptoms of phenylketonuria if used by phenylketonurics. L-phenylalanine was reported to exacerbate tardive dyskinesia when used by some with schizophrenia. (en)
http://linked.open...ynthesisReference	Gerald L. Bachman, "Recovery of L-phenylalanine and L-aspartic acid during preparation of .alpha.-L-aspartyl-L-phenylalanine methyl ester." U.S. Patent US4348317, issued January, 1967. (en)
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foaf:page	http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/lph_0201.shtml
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http://linked.open...ugbank/absorption	Absorbed from the small intestine by a sodium dependent active transport process. (en)
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	63-91-2 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	HydrOXYzine Pamoate 50 mg capsule
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