About: Determinants of Circulating Matrix Metalloproteinase-2 and Pregnancy-Associated Plasma Protein-A in Patients with Chronic Kidney Disease     Goto   Sponge   NotDistinct   Permalink

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  • Matrix metalloproteinase-2 (MMP-2) and pregnancy-associated plasma protein-A (PAPP-A) have been implicated in chronic kidney disease (CKD) and cardiovascular disease (CVD). However, the serum determinants of MMP-2 and PAPP-A in CKD are unknown. The aim of the present study is to evaluate the clinical significance of MMP-2 and PAPP-A and their determinants in patients with CKD. The present study demonstrated that serum MMP-2 and PAPP-A were independent correlates of proteinuria, albumin, and other examined parameters. Our results suggest the possibility that circulating MMP-2 and PAPP-A be used as indicators for renal damage in CKD patients on conservative treatment.
  • Matrix metalloproteinase-2 (MMP-2) and pregnancy-associated plasma protein-A (PAPP-A) have been implicated in chronic kidney disease (CKD) and cardiovascular disease (CVD). However, the serum determinants of MMP-2 and PAPP-A in CKD are unknown. The aim of the present study is to evaluate the clinical significance of MMP-2 and PAPP-A and their determinants in patients with CKD. The present study demonstrated that serum MMP-2 and PAPP-A were independent correlates of proteinuria, albumin, and other examined parameters. Our results suggest the possibility that circulating MMP-2 and PAPP-A be used as indicators for renal damage in CKD patients on conservative treatment. (en)
Title
  • Determinants of Circulating Matrix Metalloproteinase-2 and Pregnancy-Associated Plasma Protein-A in Patients with Chronic Kidney Disease
  • Determinants of Circulating Matrix Metalloproteinase-2 and Pregnancy-Associated Plasma Protein-A in Patients with Chronic Kidney Disease (en)
skos:prefLabel
  • Determinants of Circulating Matrix Metalloproteinase-2 and Pregnancy-Associated Plasma Protein-A in Patients with Chronic Kidney Disease
  • Determinants of Circulating Matrix Metalloproteinase-2 and Pregnancy-Associated Plasma Protein-A in Patients with Chronic Kidney Disease (en)
skos:notation
  • RIV/68407700:21230/12:00198587!RIV13-MSM-21230___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, S, V
http://linked.open...iv/cisloPeriodika
  • 5-6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
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  • 130529
http://linked.open...ai/riv/idVysledku
  • RIV/68407700:21230/12:00198587
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Matrix metalloproteinase-2; pregnancy-associated plasma protein-A; Chronic Kidney disease; proteinuria; albumin; anaemia (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [383503F1864C]
http://linked.open...i/riv/nazevZdroje
  • CLINICAL LABORATORY
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 58
http://linked.open...iv/tvurceVysledku
  • Kříha, Vítězslav
  • Kalousová, M.
  • Zima, T.
  • Kratochvilová, M.
  • Tesar, V.
  • Zakiyanov, O.
http://linked.open...ain/vavai/riv/wos
  • 000305711100013
issn
  • 1433-6510
number of pages
http://localhost/t...ganizacniJednotka
  • 21230
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