About: On the interaction between [Ru(NH3)(6)](3+) and the G-quadruplex forming thrombin binding aptamer sequence     Goto   Sponge   NotDistinct   Permalink

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  • The interaction between the thrombin binding aptamer (TBA), a G-quadruplex forming DNA sequence, and the electroactive hexaammineruthenium(III) cation has been studied by electrochemical methods and circular dichroism spectroscopy. When TBA is immobilised on a gold surface in a typical aptasensor configuration, the [Ru(NH3)(6)](3+) cation can be bound to the electrode surface through its interaction with the TBA sequence. This interaction is strong enough to enable-the-ruthenium complex-to remain at the surface when the electrode is immersed in an electrolyte free of [Ru(NH3)(6)](3+), meaning that the complex does not diffuse back into the solution.
  • The interaction between the thrombin binding aptamer (TBA), a G-quadruplex forming DNA sequence, and the electroactive hexaammineruthenium(III) cation has been studied by electrochemical methods and circular dichroism spectroscopy. When TBA is immobilised on a gold surface in a typical aptasensor configuration, the [Ru(NH3)(6)](3+) cation can be bound to the electrode surface through its interaction with the TBA sequence. This interaction is strong enough to enable-the-ruthenium complex-to remain at the surface when the electrode is immersed in an electrolyte free of [Ru(NH3)(6)](3+), meaning that the complex does not diffuse back into the solution. (en)
Title
  • On the interaction between [Ru(NH3)(6)](3+) and the G-quadruplex forming thrombin binding aptamer sequence
  • On the interaction between [Ru(NH3)(6)](3+) and the G-quadruplex forming thrombin binding aptamer sequence (en)
skos:prefLabel
  • On the interaction between [Ru(NH3)(6)](3+) and the G-quadruplex forming thrombin binding aptamer sequence
  • On the interaction between [Ru(NH3)(6)](3+) and the G-quadruplex forming thrombin binding aptamer sequence (en)
skos:notation
  • RIV/68081707:_____/13:00399496!RIV14-AV0-68081707
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
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  • I
http://linked.open...iv/cisloPeriodika
  • SEP 2013
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  • 93892
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  • RIV/68081707:_____/13:00399496
http://linked.open...riv/jazykVysledku
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  • SELF-ASSEMBLED MONOLAYERS; DNA-MODIFIED SURFACES; CIRCULAR-DICHROISM (en)
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  • US - Spojené státy americké
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  • [2BDF97A6D10E]
http://linked.open...i/riv/nazevZdroje
  • Journal of Inorganic Biochemistry
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  • 126
http://linked.open...iv/tvurceVysledku
  • Doneux, T.
  • Kejnovská, Iva
  • Buess-Herman, C.
  • De Rache, A.
http://linked.open...ain/vavai/riv/wos
  • 000322942400012
issn
  • 0162-0134
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.jinorgbio.2013.05.014
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