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  • There is a growing interest in using semiconductor quantum dots (QDs) as optical labels for biosensing events. The size-controlled fluorescence properties of QDs, the high fluorescence quantum yields of QDs and their stability against photobleaching makes QDs superior optical labels for multiplex analysis. In this paper, biotin-conjugated glutathione (B-GSH) was synthesized using peptide bonding of the biotin carboxy group and amino group of the glutamic acid to create an alternative coating for CdTe QDs. This type of coating combines the functionality of biotin with the fluorescent properties of quantum dots to create a specific, high affinity fluorescent probe able to react with avidin, streptavidin and/or neutravidin. Biotin-funcionalized glutathione-coated QDs were prepared by a facile one step reduction route using Na2TeO3 as the Te source in an aqueous environment. The synthesis parameters of this simple and rapid approach, including the reaction temperature and time, the pH of the reaction s
  • There is a growing interest in using semiconductor quantum dots (QDs) as optical labels for biosensing events. The size-controlled fluorescence properties of QDs, the high fluorescence quantum yields of QDs and their stability against photobleaching makes QDs superior optical labels for multiplex analysis. In this paper, biotin-conjugated glutathione (B-GSH) was synthesized using peptide bonding of the biotin carboxy group and amino group of the glutamic acid to create an alternative coating for CdTe QDs. This type of coating combines the functionality of biotin with the fluorescent properties of quantum dots to create a specific, high affinity fluorescent probe able to react with avidin, streptavidin and/or neutravidin. Biotin-funcionalized glutathione-coated QDs were prepared by a facile one step reduction route using Na2TeO3 as the Te source in an aqueous environment. The synthesis parameters of this simple and rapid approach, including the reaction temperature and time, the pH of the reaction s (en)
Title
  • Synthesis and modification of quantum dots for medical applications
  • Synthesis and modification of quantum dots for medical applications (en)
skos:prefLabel
  • Synthesis and modification of quantum dots for medical applications
  • Synthesis and modification of quantum dots for medical applications (en)
skos:notation
  • RIV/00216305:26220/11:PU95488!RIV12-GA0-26220___
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  • P(GAP102/11/1068), P(KAN208130801)
http://linked.open...vai/riv/dodaniDat
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  • 233874
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  • RIV/00216305:26220/11:PU95488
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http://linked.open.../riv/klicovaSlova
  • quantum dots, modification (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [EACBF1B325D6]
http://linked.open...v/mistoKonaniAkce
  • Brno
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  • Neuveden
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  • NANOCON 2011 - sborník příspěvků
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  • Adam, Vojtěch
  • Chomoucká, Jana
  • Drbohlavová, Jana
  • Hubálek, Jaromír
  • Janů, Libor
  • Kizek, René
  • Prášek, Jan
  • Ryvolová, Markéta
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
number of pages
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  • TANGER spol. s r.o.
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  • 978-80-87294-23-9
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  • 26220
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