About: Similar circuits but different connectivity patterns between the cerebellum, Basal Ganglia, and supplementary motor area in early Parkinson's disease patients and controls during predictive motor timing

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About: Similar circuits but different connectivity patterns between the cerebellum, Basal Ganglia, and supplementary motor area in early Parkinson's disease patients and controls during predictive motor timing Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://onlinelibrary.wiley.com/doi/10.1111/jon.12030/pdf
Description	The cerebellum, basal ganglia (BG), and other cortical regions, such as supplementary motor area (SMA) have emerged as important structures dealing with various aspects of timing, yet the modulation of functional connectivity between them during motor timing tasks remains unexplored. METHODS: We used dynamic causal modeling to investigate the differences in effective connectivity (EC) between these regions and its modulation by behavioral outcome during a motor timing prediction task in a group of 16 patients with early Parkinson's disease (PD) and 17 healthy controls. Behavioral events (hits and errors) constituted the driving input connected to the cerebellum, and the modulation in connectivity was assessed relative to the hit condition (successful interception of target). RESULTS: The driving input elicited response in the target area, while modulatory input changed the specific connection strength. The cerebellum, basal ganglia (BG), and other cortical regions, such as supplementary motor area (SMA) have emerged as important structures dealing with various aspects of timing, yet the modulation of functional connectivity between them during motor timing tasks remains unexplored. METHODS: We used dynamic causal modeling to investigate the differences in effective connectivity (EC) between these regions and its modulation by behavioral outcome during a motor timing prediction task in a group of 16 patients with early Parkinson's disease (PD) and 17 healthy controls. Behavioral events (hits and errors) constituted the driving input connected to the cerebellum, and the modulation in connectivity was assessed relative to the hit condition (successful interception of target). RESULTS: The driving input elicited response in the target area, while modulatory input changed the specific connection strength. (en)
Title	Similar circuits but different connectivity patterns between the cerebellum, Basal Ganglia, and supplementary motor area in early Parkinson's disease patients and controls during predictive motor timing Similar circuits but different connectivity patterns between the cerebellum, Basal Ganglia, and supplementary motor area in early Parkinson's disease patients and controls during predictive motor timing (en)
skos:prefLabel	Similar circuits but different connectivity patterns between the cerebellum, Basal Ganglia, and supplementary motor area in early Parkinson's disease patients and controls during predictive motor timing Similar circuits but different connectivity patterns between the cerebellum, Basal Ganglia, and supplementary motor area in early Parkinson's disease patients and controls during predictive motor timing (en)
skos:notation	RIV/00216224:14740/13:00069968!RIV14-MSM-14740___
http://linked.open...avai/predkladatel	Středoevropský technologický institut
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Mikl, Michal Bareš, Martin Mareček, Radek Vaníček, Jiří Husárová, Ivica
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	105100
http://linked.open...ai/riv/idVysledku	RIV/00216224:14740/13:00069968
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Basal ganglia; Parkinson's disease; cerebellum; connectivity; cortical reorganization; motor timing; prediction; supplementary motor area (en)
http://linked.open.../riv/klicoveSlovo	cortical reorganization Basal ganglia Parkinson's disease connectivity prediction motor timing cerebellum supplementary motor area
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[B39CCEF4EB9E]
http://linked.open...i/riv/nazevZdroje	Journal of Neuroimaging
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	23
http://linked.open...iv/tvurceVysledku	Bareš, Martin Mikl, Michal Mareček, Radek Vaníček, Jiří Lungu, Ovidiu V. Husárová, Ivica
issn	1051-2284
number of pages	11 (xsd:int)
http://bibframe.org/vocab/doi	10.1111/jon.12030
http://localhost/t...ganizacniJednotka	14740

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