About: Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://worldwide.espacenet.com/publicationDetails/biblio?CC=EP&NR=2602330
Description	The present invention relates to a method for determining the sensitivity and/or resistance of a patient suffering from a cancer disease to Aurora kinase inhibitor therapy, which comprises determining in vitro in the cancer cells or body fluids taken from the patient the expression of at least one gene selected from a particular group and/or determining in vitro in the cancer cells or body fluids taken from the patient the level of at least one protein selected from a particular group. Also, the invention relates to a group of compounds which allow overcoming the resistance. The present invention relates to a method for determining the sensitivity and/or resistance of a patient suffering from a cancer disease to Aurora kinase inhibitor therapy, which comprises determining in vitro in the cancer cells or body fluids taken from the patient the expression of at least one gene selected from a particular group and/or determining in vitro in the cancer cells or body fluids taken from the patient the level of at least one protein selected from a particular group. Also, the invention relates to a group of compounds which allow overcoming the resistance. (en)
Title	Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance (en)
skos:prefLabel	Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance (en)
skos:notation	RIV/67985904:_____/13:00442717!RIV15-AV0-67985904
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(ED2.1.00/03.0124)
http://linked.open...cisloPatentuVzoru	EP2602330 (A1)
http://linked.open...eleniPatentuVzoru	2013-06-12 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Kovářová, Hana Hrabáková, Rita
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	87557
http://linked.open...ai/riv/idVysledku	RIV/67985904:_____/13:00442717
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cancer cell drug sensitivity; Aurora Kinase (en)
http://linked.open.../riv/klicoveSlovo	Aurora Kinase cancer cell drug sensitivity
http://linked.open...ontrolniKodProRIV	[B85403C02EF1]
http://linked.open.../licencniPoplatek	A - Poskytovatel licence na výsledek požaduje licenční poplatek
http://linked.open...ydaniPatentuVzoru	Munich, The Hague, Berlin, Vienna, Brussels
http://linked.open...atelePatentuVzoru	Evropský patentový úřad
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	ExAM Experimental Animal Models
http://linked.open...UplatneniVysledku	2013
http://linked.open...iv/tvurceVysledku	Hrabáková, Rita Kovářová, Hana Džubák, P. Hajdúch, M. Srovnal, J. Kollareddy, M. R.
http://linked.open...mniOchranaPatentu	A - EPO (Evropský patentový úřad)
http://linked.open...avai/riv/vlastnik	Univerzita Palackého v Olomouci, Ústav živočišné fyziologie a genetiky AV ČR, v. v. i
http://linked.open...itiJinymSubjektem	A - Nabytí licence je nutné vždy
http://linked.open...uzitiPatentuVzoru	B - Využívaný třetí stranou na základě licenční smlouvy
http://linked.open...stnikPatentuVzoru	Univerzita Palackého v Olomouci, Ústav živočišné fyziologie a genetiky AV ČR, v. v. i

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