About: Genetics of Cd36 and the hypertension metabolic syndrome

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Zjištěním, že zmutovaný Cd36 přispívá k patogenezi poruch metabolizmu glukózy a lipidů u zvířecích modelů i u lidí by mohlo být využito pro zlepšení terapie metabolického syndromu, protože Cd36 je cílovýn genem pro PPAR?, ligandami aktivovaný transkripční faktor, který reguluje expresi řady genů důležitých pro metabolizmus glukózy a lipidů (cs) The discovery that defective Cd36 can contribute to the pathogenesis of disordered carbohydrate and lipid metabolism in animal models and in humans may have implications for developing improved approaches to the treatment of metabolic syndrome since Cd36 is a target gene for the PPAR?, a ligand activated transcription factor that regulates the expression of a number of genes involved in carbohydrate and lipid metabolism The discovery that defective Cd36 can contribute to the pathogenesis of disordered carbohydrate and lipid metabolism in animal models and in humans may have implications for developing improved approaches to the treatment of metabolic syndrome since Cd36 is a target gene for the PPAR?, a ligand activated transcription factor that regulates the expression of a number of genes involved in carbohydrate and lipid metabolism (en)
Title	Genetics of Cd36 and the hypertension metabolic syndrome Genetics of Cd36 and the hypertension metabolic syndrome (en) Genetika Cd36, hypertenze a metabolický syndrom (cs)
skos:prefLabel	Genetics of Cd36 and the hypertension metabolic syndrome Genetics of Cd36 and the hypertension metabolic syndrome (en) Genetika Cd36, hypertenze a metabolický syndrom (cs)
skos:notation	RIV/67985823:_____/02:00142307!RIV07-AV0-67985823
http://linked.open.../vavai/riv/strany	148;153
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA301/00/1636), P(GV204/98/K015), P(LN00A079), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Pravenec, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	646980
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/02:00142307
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cd36 (en)
http://linked.open.../riv/klicoveSlovo	Cd36
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[FBC07C12D4FC]
http://linked.open...i/riv/nazevZdroje	Seminars in Nephrology
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Analysis of the effects of Cd36 (fat) transgene in spontaneously hypertensive rats on clustering of cardiovascular risk factors Center of Integrated Genomics Molecular mapping of the mammalian genome and positional cloning of mammalian genes
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	22
http://linked.open...iv/tvurceVysledku	Pravenec, Michal Kurtz, W. T.
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0270-9295
number of pages	6 (xsd:int)

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