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Description
  • The antibiotic lincomycin and its derivatives are active against Gram-positive bacteria and protozoans. Lincomycin and its chlorinated derivative clindamycin, which is more active than lincomycin, are widely used in medicine, often in combination with other antibiotic or nonantibiotic antimicrobials. Resistance to lincomycin and clindamycin may be caused by several mechanisms. The review describes the chemical structure of lincosamide antibiotics, analytical procedures used for their identification, separation and isolation and the biosynthesis of lincomycin and related compounds and its genetic control
  • The antibiotic lincomycin and its derivatives are active against Gram-positive bacteria and protozoans. Lincomycin and its chlorinated derivative clindamycin, which is more active than lincomycin, are widely used in medicine, often in combination with other antibiotic or nonantibiotic antimicrobials. Resistance to lincomycin and clindamycin may be caused by several mechanisms. The review describes the chemical structure of lincosamide antibiotics, analytical procedures used for their identification, separation and isolation and the biosynthesis of lincomycin and related compounds and its genetic control (en)
  • Antibiotikum linkomycin a jeho deriváty působí hlavně proti Gram-pozitivním bakteriím a prvokům. Linkomycin a jeho chlorovaný derivát klindamycin, který je aktivnější než linkomycin, mají široké použití v medicině, často v kombinaci s jinými antibiotiky nebo neantibiotickými antimikrobiálními látkami Resistence k linkomycinu a klindamycin může být způsobena různými mechanismy. Článek popisuje chemickou strukturu linkosamidových antibiotik, analytické metody jejich identifikace, separace a isolace, biosyntézu linkomycinu a příbuzných látek a její genetickou kontrolu (cs)
Title
  • Medicinal Use of Lincosamides and Microbial Resistance to Them
  • Medicinal Use of Lincosamides and Microbial Resistance to Them (en)
  • Lékařské aplikace linkosamidů a mikrobiální resistence k nim (cs)
skos:prefLabel
  • Medicinal Use of Lincosamides and Microbial Resistance to Them
  • Medicinal Use of Lincosamides and Microbial Resistance to Them (en)
  • Lékařské aplikace linkosamidů a mikrobiální resistence k nim (cs)
skos:notation
  • RIV/61388971:_____/07:00085743!RIV08-AV0-61388971
http://linked.open.../vavai/riv/strany
  • 133;144
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika
  • -
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 432675
http://linked.open...ai/riv/idVysledku
  • RIV/61388971:_____/07:00085743
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • lincomycin; clindamycin; lincosamide antibiotics (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [55042863B7B4]
http://linked.open...i/riv/nazevZdroje
  • Anti-Infective Agents in Medicinal Chemistry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 6
http://linked.open...iv/tvurceVysledku
  • Sigler, Karel
  • Řezanka, Tomáš
  • Spížek, Jaroslav
http://linked.open...n/vavai/riv/zamer
issn
  • 1871-5214
number of pages
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