About: Oligonucleotides with isopolar phosphonate internucleotide linkage: a new perspective for antisense compounds?

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About: Oligonucleotides with isopolar phosphonate internucleotide linkage: a new perspective for antisense compounds? Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Several types of isopolar modified oligothymidylates and oligoadenylates (15 mers) with the phosphonate - O-P-CH 2 -O - internucleotide linkage were prepared. The modified oligonucleotides were subjected to the study of their hybridization properties, resistance against nucleases, and the ability to elicit RNase H activity. Several types of isopolar modified oligothymidylates and oligoadenylates (15 mers) with the phosphonate - O-P-CH 2 -O - internucleotide linkage were prepared. The modified oligonucleotides were subjected to the study of their hybridization properties, resistance against nucleases, and the ability to elicit RNase H activity. (en)
Title	Oligonucleotides with isopolar phosphonate internucleotide linkage: a new perspective for antisense compounds? Oligonucleotides with isopolar phosphonate internucleotide linkage: a new perspective for antisense compounds? (en)
skos:prefLabel	Oligonucleotides with isopolar phosphonate internucleotide linkage: a new perspective for antisense compounds? Oligonucleotides with isopolar phosphonate internucleotide linkage: a new perspective for antisense compounds? (en)
skos:notation	RIV/61388963:_____/01:57010345!RIV/2003/AV0/A57003/N
http://linked.open.../vavai/riv/strany	819;823
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(IAA4055902), P(NL5441), Z(AV0Z4055905)
http://linked.open...iv/cisloPeriodika	4/7
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Pačes, Ondřej Rinnová, Markéta Rosenberg, Ivan Rejman, Dominik Točík, Zdeněk Králíková, Šárka Liboska, Radek Snášel, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	689814
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/01:57010345
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	phosphonate oligonucleotides and RNase H (en)
http://linked.open.../riv/klicoveSlovo	phosphonate oligonucleotides and RNase H
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[818268E235B5]
http://linked.open...i/riv/nazevZdroje	Nucleosides, Nucleotides and Nucleic Acids
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Anomeric D- and L-oligonucleotides with isopolar, isosteric internucleotide linkage: Synthesis, hybridization properties and spectroscopy Novel phosphonate oligonucleotide inhibitors of retroviral integrases
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	20
http://linked.open...iv/tvurceVysledku	Rosenberg, Ivan Rejman, Dominik Králíková, Šárka Točík, Zdeněk Liboska, Radek Snášel, Jan Pačes, Ondřej Rinnová, Markéta Koiš, P.
http://linked.open...n/vavai/riv/zamer	Chemical principles of selected biological phenomena in medicine and ecology
issn	0732-8311
number of pages	5 (xsd:int)

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