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rdf:type
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Description
| - Capecitabine has been studied by a combined potentiometric and spectrophotometric titration at T = (298.15, 310.15) K at different ionic strengths. The thermodynamic dissociation constant was estimated by non-linear regression of (pK(a), I) data: pK(a)(T) = 8.97(1) at T = 298.15 K and pK(a)(T) = 8.74(0) at T = 310.15 K, where the figure in the brackets is the standard deviation in last significant digits. Thermodynamic parameters Delta H degrees/kJ.mol(-1) and Delta S degrees/J.K-1.mol(-1) have been determined from the temperature variation of thermodynamic dissociation constants. The value of enthalpy Delta H degrees = 33.9 kJ.mol(-1) shows the dissociation process is endothermic and the value of entropy Delta S degrees = -51.9J.K-1.mol(-1) indicates that the dissociation is not a spontaneous process.
- Capecitabine has been studied by a combined potentiometric and spectrophotometric titration at T = (298.15, 310.15) K at different ionic strengths. The thermodynamic dissociation constant was estimated by non-linear regression of (pK(a), I) data: pK(a)(T) = 8.97(1) at T = 298.15 K and pK(a)(T) = 8.74(0) at T = 310.15 K, where the figure in the brackets is the standard deviation in last significant digits. Thermodynamic parameters Delta H degrees/kJ.mol(-1) and Delta S degrees/J.K-1.mol(-1) have been determined from the temperature variation of thermodynamic dissociation constants. The value of enthalpy Delta H degrees = 33.9 kJ.mol(-1) shows the dissociation process is endothermic and the value of entropy Delta S degrees = -51.9J.K-1.mol(-1) indicates that the dissociation is not a spontaneous process. (en)
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Title
| - Determination of the thermodynamic dissociation constant of capecitabine using spectrophotometric and potentiometric titration data
- Determination of the thermodynamic dissociation constant of capecitabine using spectrophotometric and potentiometric titration data (en)
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skos:prefLabel
| - Determination of the thermodynamic dissociation constant of capecitabine using spectrophotometric and potentiometric titration data
- Determination of the thermodynamic dissociation constant of capecitabine using spectrophotometric and potentiometric titration data (en)
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skos:notation
| - RIV/00216275:25310/11:39883426!RIV12-MZ0-25310___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(NS9831), Z(MSM0021627502)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216275:25310/11:39883426
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - HYPERQUAD; ESAB2M; SQUAD; SPECFIT; Capecitabine; Dissociation constant; Potentiometric titration; Spectrophotometric titration (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of Chemical Thermodynamics
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Ferenčíková, Zuzana
- Meloun, Milan
- Vrána, Aleš
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.jct.2011.01.012
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http://localhost/t...ganizacniJednotka
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