About: Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4alpha upregulation in primary human hepatocytes

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About: Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4alpha upregulation in primary human hepatocytes Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.if-pan.krakow.pl/pjp/pdf/2013/5_1322.pdf
Description	We can conclude that GR-induced expression of HNF4 alpha may contribute to indirect OCT1 gene up-regulation by dexamethasone in primary human hepatocytes, but not in hepatocyte-derived tumor cell lines. We can conclude that GR-induced expression of HNF4 alpha may contribute to indirect OCT1 gene up-regulation by dexamethasone in primary human hepatocytes, but not in hepatocyte-derived tumor cell lines. (en)
Title	Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4alpha upregulation in primary human hepatocytes Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4alpha upregulation in primary human hepatocytes (en)
skos:prefLabel	Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4alpha upregulation in primary human hepatocytes Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4alpha upregulation in primary human hepatocytes (en)
skos:notation	RIV/00216208:11160/13:10146003!RIV14-GA0-11160___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GAP303/12/0472), P(GBP303/12/G163)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Smutný, Tomáš Pávek, Petr Rulcová, Alice Krausová, Lucie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	76705
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/13:10146003
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	hepatocyte; gene regulation; C/EBP beta; HNF4 alpha; glucocorticoid receptor; OCT1 transporter (en)
http://linked.open.../riv/klicoveSlovo	gene regulation C/EBP beta HNF4 alpha OCT1 transporter glucocorticoid receptor hepatocyte
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[3321310AB875]
http://linked.open...i/riv/nazevZdroje	Pharmacological Reports
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Novel mechanisms of CYP3A4 enzyme regulation based on posttranslational modification of nuclear receptors - implications for pharmacotherapy Centre of drug-dietary supplements interactions and nutrigenetics
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	65
http://linked.open...iv/tvurceVysledku	Dvořák, Zdeněk Pávek, Petr Vrzal, Radim Krausová, Lucie Rulcová, Alice Jover, Ramiro Smutný, Tomáš
http://linked.open...ain/vavai/riv/wos	000330815700028
issn	1734-1140
number of pages	14 (xsd:int)
http://localhost/t...ganizacniJednotka	11160

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