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Description
| - Water-soluble chitosan conjugates were prepared by connection with isoniazid, pyrazinamide and ethionamide across the O-carboxymethyl and N-succinyl bridge followed by phosphorylation. Their structures were characterized by FTIR and (1)H NMR spectroscopy. Degree of drug substitution and molecular weight of prepared compounds have been investigated. Antimycobacterial activity was determined against Mycobacterium tuberculosis and three non-tuberculosis strains.
- Water-soluble chitosan conjugates were prepared by connection with isoniazid, pyrazinamide and ethionamide across the O-carboxymethyl and N-succinyl bridge followed by phosphorylation. Their structures were characterized by FTIR and (1)H NMR spectroscopy. Degree of drug substitution and molecular weight of prepared compounds have been investigated. Antimycobacterial activity was determined against Mycobacterium tuberculosis and three non-tuberculosis strains. (en)
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Title
| - Cytotoxicity decreasing effect and antimycobacterial activity of chitosan conjugated with antituberculotic drugs
- Cytotoxicity decreasing effect and antimycobacterial activity of chitosan conjugated with antituberculotic drugs (en)
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skos:prefLabel
| - Cytotoxicity decreasing effect and antimycobacterial activity of chitosan conjugated with antituberculotic drugs
- Cytotoxicity decreasing effect and antimycobacterial activity of chitosan conjugated with antituberculotic drugs (en)
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skos:notation
| - RIV/00216208:11160/11:10099482!RIV12-MZ0-11160___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(NS10367), S, Z(MSM0021620822)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11160/11:10099482
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Cytotoxicity; In vitro antimycobacterial activity; Ethionamide; Pyrazinamide; Isoniazid; Chitosan (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Vavříková, Eva
- Vinšová, Jarmila
- Bősze, Szilvia
- Horváti, Kata
- Mandíková, Jana
- Stolaříková, Jiřina
- Trejtnar, František
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.carbpol.2010.10.053
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http://localhost/t...ganizacniJednotka
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