About: Levalbuterol Tartrate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Levalbuterol Tartrate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Levalbuterol Tartrate
UMLS_CUI
  • C1576818
CAS_Registry
  • 661464-94-4
FDA_UNII_Code
  • ADS4I3E22M
Contributing_Source
  • FDA
Chemical_Formula
  • 2C13H21NO3.C4H6O6
Legacy_Concept_Name
  • Levalbuterol_Tartrate
FULL_SYN
  • LEVALBUTEROL TARTRATEPTFDAADS4I3E22M
  • Levalbuterol TartratePTNCI
DEFINITION
  • The tartrate salt form of levalbuterol, the R-enantiomer of the short-acting beta-2 adrenergic receptor agonist albuterol, with bronchodilator activity. Levalbuterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells.NCI
code
  • C66003
is Has_Salt_Form of
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