About: Binetrakin

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Binetrakin
rdfs:subClassOf	Recombinant Interleukin nodeID://b719355 nodeID://b719356 nodeID://b719357 nodeID://b719358 nodeID://b719359 nodeID://b719360 nodeID://b719361
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance Immunologic Factor
Preferred_Name	Binetrakin
NSC_Code	618085 620211
UMLS_CUI	C1522540
CAS_Registry	207137-56-2
In_Clinical_Trial_For	HLA A2.1 positive colorectal cancer; metastatic melanoma; metastatic sarcoma; Non-small cell lung cancer
FDA_UNII_Code	751635Z921
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	39324
PDQ_Closed_Trial_Search_ID	39324
Legacy_Concept_Name	Therapeutic_Interleukin-4
FULL_SYN	BinetrakinPTNCI T-Cell Growth Factor 2SYNCI IL-4PTNCI-GLOSSCDR0000044420 Mast Cell Growth Factor-2SYNCI B-Cell Stimulating FactorSYNCI BCGFABNCI B-Cell Stimulatory Factor 1SYNCI B Cell Proliferating FactorSYNCI BCSF 1ABNCI MCGF 2ABNCI B-Cell Growth FactorSYNCI RHIL-4ABNCI Recombinant Human IL-4SYNCI Interleukin-4SYNCI Interleukin-4SYDTPNSC0618085 IL-4ABNCI BINETRAKINPTFDA751635Z921
DEFINITION	A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T-cells, IL-4 binds to and activates its cell-surface receptor, stimulating the proliferation and differentiation of activated B-cells and enhancing their ability to present antigens to T-cells. As a potential immunotherapeutic agent, recombinant IL-4 also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL).NCI
code	C589
is someValuesFrom of	nodeID://b647675 nodeID://b683730 nodeID://b683733

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