About: Ethacrynic Acid     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Ethacrynic Acid
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Ethacrynic Acid
NSC_Code
  • 85791
UMLS_CUI
  • C0014963
CAS_Registry
  • 58-54-8
FDA_UNII_Code
  • M5DP350VZV
Contributing_Source
  • FDA
ALT_DEFINITION
  • A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 41163
PDQ_Closed_Trial_Search_ID
  • 41163
Chemical_Formula
  • C13H12Cl2O4
Legacy_Concept_Name
  • Ethacrynic_Acid
CHEBI_ID
  • CHEBI:4876
FULL_SYN
  • [2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic AcidPTDCP05221
  • EAABNCI
  • ETHACRYNIC ACIDPTFDAM5DP350VZV
  • Ethacrynic AcidPTNCI
  • EdecrinSYDTPNSC0085791
  • Ethacrynic acidSYDTPNSC0624008
  • EdecrinBRNCI
  • [2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic AcidSNNCI
DEFINITION
  • An unsaturated ketone derivative of aryloxyacetic acid without a sulfonamide substituent belonging to the class of loop diuretics. Ethacrynic acid is extensively bound to plasma proteins; both ethacrynic acid in its unchanged form as well as its metabolites are excreted in bile and urine.NCI
code
  • C485
is someValuesFrom of
is Has_Free_Acid_Or_Base_Form of
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