About: Ibutilide Fumarate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Ibutilide Fumarate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ibutilide Fumarate
UMLS_CUI
  • C0644117
CAS_Registry
  • 122647-32-9
FDA_UNII_Code
  • 9L5X4M5L6I
Contributing_Source
  • FDA
Chemical_Formula
  • 2C20H36N2O3S.C4H4O4
Legacy_Concept_Name
  • Ibutilide_Fumarate
FULL_SYN
  • Ibutilide FumaratePTNCI
  • CorvertBRNCI
  • IBUTILIDE FUMARATEPTFDA9L5X4M5L6I
  • (+-)-4'-(4-(Ethylheptylamino)-1-hydroxybutyl)methanesulfonanilide Fumarate(2:1)(salt)SNNCI
DEFINITION
  • The fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outward potassium currents. This results in prolongation of atrial and ventricular action potential duration and refractory periods. Ibutilide slightly decreases the sinus rate and atrioventricular (AV) conduction and produces a dose-related prolongation of the QT interval. (NCI05)NCI
code
  • C47561
is Has_Salt_Form of
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