About: Hydroxyzine Pamoate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Hydroxyzine Pamoate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Hydroxyzine Pamoate
UMLS_CUI
  • C0700539
CAS_Registry
  • 10246-75-0
FDA_UNII_Code
  • M20215MUFR
Contributing_Source
  • FDA
Chemical_Formula
  • C23H16O6.C21H27ClN2O2
Legacy_Concept_Name
  • Hydroxyzine_Pamoate
CHEBI_ID
  • CHEBI:31680
FULL_SYN
  • 2-Naphthoic Acid, 4,4'-methylenebis(3-hydroxy-, ester with 2-(2-(4-(p-chloro-alpha-phenylbenzyl)-1-piperazinyl)-ethoxy)ethanolSNNCI
  • Hydroxyzine PamoatePTNCI
  • Atarax PSYNCI
  • MasmoranSYNCI
  • VistarilBRNCI
  • PaxistilSYNCI
  • HYDROXYZINE PAMOATEPTFDAM20215MUFR
  • Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, compound with 4,4'-Methylenebis(3-hydroxy-2-naphthalenecarboxylic Acid)(1:1)SNNCI
DEFINITION
  • The pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine pamoate blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. In addition, hydroxyzine pamoate crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system. (NCI05)NCI
code
  • C47560
is Has_Salt_Form of
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