About: Elongation Factor 1D     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Elongation Factor 1D
equivalentClass
OMIM_Number
  • 130592
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Elongation Factor 1D
UMLS_CUI
  • C1527079
Legacy_Concept_Name
  • Elongation_Factor-1D
FULL_SYN
  • Guanine Nucleotide Exchange ProteinSYNCI
  • Elongation Factor-1-DeltaSYNCI
  • Antigen NY-CO-4SYNCI
  • EEF1DSYNCI
  • Eukaryotic Translation Elongation Factor 1 DeltaSYNCI
  • Elongation Factor 1DPTNCI
  • EF-1-DeltaSYNCI
Swiss_Prot
  • P29692
DEFINITION
  • Encoded by human EEF1D Gene (EF1Beta/EF1Delta Family), 281-aa 31-kDa Elongation Factor 1D is a subunit of heterotrimeric Elongation Factor 1 (containing alpha/beta/gamma or alpha/delta/gamma subunits). Composed of an alpha subunit nucleotide binding domain and a beta/gamma subunit nucleotide exchange complex, Elongation Factor 1 is responsible for delivery of aminoacyl tRNAs to the ribosome. The homologous guanine nucleotide exchange factor EF-1-delta and EF-1-beta subunits stimulate GDP/GTP exchange bound to EF-1-alpha; phosphorylation affects the GDP/GTP exchange rate. EEF1D may interact with HIV-1 Tat and repress host-cell mRNA translation. (NCI)NCI
code
  • C38964
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