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AttributesValues
rdf:type
rdfs:label
  • Aminoglutethimide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Aminoglutethimide
NSC_Code
  • 330915
UMLS_CUI
  • C0002555
CAS_Registry
  • 125-84-8
FDA_UNII_Code
  • 0O54ZQ14I9
Contributing_Source
  • FDA
ALT_DEFINITION
  • An anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors. Aminoglutethimide is used to decrease the production of sex hormones (estrogen in women or testosterone in men) and suppress the growth of tumors that need sex hormones to grow.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39140
PDQ_Closed_Trial_Search_ID
  • 39140
Chemical_Formula
  • C13H16N2O2
Legacy_Concept_Name
  • Aminoglutethimide
CHEBI_ID
  • CHEBI:2654
FULL_SYN
  • aminoglutethimidePTNCI-GLOSSCDR0000045170
  • AminoblastinFBNCI
  • AminoglutethimidePTDCP00407
  • alpha-(4-Aminophenyl)-alpha-ethylglutarimideSNNCI
  • 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedioneSNNCI
  • 3-Ethyl-3-(p-aminophenyl)-2,6-dioxopiperidineSNNCI
  • 2-(p-Aminophenyl)-2-ethylglutarimideSNNCI
  • Ba-16038SYDTPNSC0330915
  • EliptenSYDTPNSC0330915
  • 2-(p-Aminophenyl)-2-ethylglutarimideSYDTPNSC0330915
  • AminoglutethimidePTNCI
  • AminoglutethimideSYNCI
  • AMINOGLUTETHIMIDEPTFDA0O54ZQ14I9
  • MamomitFBNCI
  • EliptenSYNCI
  • RodazolFBNCI
  • BA-16038CNNCI
  • CytadrenBRNCI
  • OrimetenFBNCI
  • AminoglutethimideSYDTPNSC0330915
  • OrimeteneFBNCI
  • OrimentenSYNCI
DEFINITION
  • A synthetic derivative of the sedative and anticonvulsant glutethimide with anti-steroid properties. Originally used as an anticonvulsant, aminoglutethimide also blocks adrenal steroidogenesis by inhibiting the enzymatic conversion of cholesterol to pregnenolone. In addition, this agent blocks the peripheral aromatization of androgenic precursors to estrogens. Aminoglutethimide does not suppress ovarian estrogen production.NCI
code
  • C233
is someValuesFrom of
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