About: Glipizide

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	An oral hypoglycemic agent which is rapidly absorbed and completely metabolized. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B5E75-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5E76-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5E6F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5E70-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5E71-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5E72-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5E73-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5E74-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	2-5 hours (en)
http://linked.open...ugbank/indication	For use as an adjunct to diet for the control of hyperglycemia and its associated symptomatology in patients with non-insulin-dependent diabetes mellitus (NIDDM; type II), formerly known as maturity-onset diabetes, after an adequate trial of dietary therapy has proved unsatisfactory. (en)
sameAs	Glipizide
Title	Glipizide (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB01067/identifier/bindingdb/50012956 http://linked.opendata.cz/resource/drugbank/drug/DB01067/identifier/chemspider/3359 http://linked.opendata.cz/resource/drugbank/drug/DB01067/identifier/drugbank/DB01067 http://linked.opendata.cz/resource/drugbank/drug/DB01067/identifier/kegg-drug/D00335 http://linked.opendata.cz/resource/drugbank/drug/DB01067/identifier/national-drug-code-directory/0378-1105-01 http://linked.opendata.cz/resource/drugbank/drug/DB01067/identifier/pharmgkb/PA449762 http://linked.opendata.cz/resource/drugbank/drug/DB01067/identifier/pubchem-compound/3478 http://linked.opendata.cz/resource/drugbank/drug/DB01067/identifier/pubchem-substance/46505865 http://linked.opendata.cz/resource/drugbank/drug/DB01067/identifier/wikipedia/Glipizide
http://linked.open...mechanismOfAction	Sulfonylureas likely bind to ATP-sensitive potassium-channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the membrane. Depolarization stimulates calcium ion influx through voltage-sensitive calcium channels, raising intracellular concentrations of calcium ions, which induces the secretion, or exocytosis, of insulin. (en)
http://linked.open...drugbank/packager	APP Pharmaceuticals A-S Medication Solutions LLC Astellas Pharma Inc. Baxter International Inc. Abbott Laboratories Ltd. Ben Venue Laboratories Inc. Catalent Pharma Solutions Gland Pharma Ltd. Hospira Inc. Major Pharmaceuticals Abbott laboratories pharmaceutical products div Abbott laboratories Medvantx Inc. Murfreesboro Pharmaceutical Nursing Supply Mylan Astellas pharma us inc Akorn inc App pharmaceuticals llc Baxter healthcare corp PCA LLC Baxter International Inc. Pfizer Inc. Pharmaceutical Utilization Management Program VA Inc. Iroko Pharmaceuticals Pharmedix Orion Corporation Preferred Pharmaceuticals Inc. Prepackage Specialists Prepak Systems Inc. Actavis Group Advanced Pharmaceutical Services Inc. Alphapharm Party Ltd. Amerisource Health Services Corp. Apotex Inc. Apotheca Inc. AQ Pharmaceuticals Inc. A-S Medication Solutions LLC Merck & Co. Atlantic Biologicals Corporation Bristol-Myers Squibb Co. Bryant Ranch Prepack ALK-Abello Inc. Allergy Laboratories Inc. Coupler Enterprises Inc. Dept Health Central Pharmacy Direct Dispensing Inc. Dispensing Solutions Diversified Healthcare Services Inc. Qualitest Rebel Distributors Corp. Remedy Repack Resource Optimization and Innovation LLC Sandhills Packaging Inc. Sandoz Southwood Pharmaceuticals Stat Rx Usa Stat Scripts LLC Teva Pharmaceutical Industries Ltd. Torpharm Inc. UDL Laboratories United Research Laboratories Inc. US Pharmaceutical Group Va Cmop Dallas Vangard Labs Inc. Watson Pharmaceuticals
http://linked.open...y/drugbank/patent	http://linked.opendata.cz/resource/drugbank/patent/2024502 http://linked.opendata.cz/resource/drugbank/patent/5024843 http://linked.opendata.cz/resource/drugbank/patent/5591454
http://linked.open...outeOfElimination	The primary metabolites are inactive hydroxylation products and polar conjugates and are excreted mainly in the urine. (en)
http://linked.open.../drugbank/synonym	Aldiab (en) Digrin (en) Dipazide (en) Glibenese (en) Glibetin (en) Glican (en)

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