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AttributesValues
rdf:type
rdfs:label
  • Atinumab
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Immunologic Factor
Preferred_Name
  • Atinumab
NCI_META_CUI
  • CL430552
CAS_Registry
  • 1226761-65-4
FDA_UNII_Code
  • 9UBQ62RW32
Contributing_Source
  • FDA
FULL_SYN
  • Immunoglobulin G4-Kappa, Anti-[Homo sapiens RTN4 (Reticulon 4, Neurite Outgrowth Inhibitor, NOGO), Isoform A], Homo sapiens Monoclonal AntibodySYNCI
  • ATINUMABPTFDA9UBQ62RW32
  • ATI355CNNCI
  • 6A3-IgG4ABNCI
  • AtinumabPTNCI
DEFINITION
  • A monoclonal antibody directed against reticulon-4, with immunomodulating activity. Atinumab binds to reticulon-4, stimulating neurite outgrowth, which may prevent neuronal damage or may facilitate the regeneration of damaged neurons. Reticulon-4, also called Neurite outgrowth inhibitor or Nogo, is an inhibitor of neurite outgrowth and may prevent neuronal regeneration in the central nervous system.NCI
code
  • C97942
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