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AttributesValues
rdf:type
rdfs:label
  • Racotumomab
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Racotumomab
NCI_META_CUI
  • CL426558
CAS_Registry
  • 946832-34-4
FDA_UNII_Code
  • 52G405U1E5
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 689646
PDQ_Closed_Trial_Search_ID
  • 689646
FULL_SYN
  • RacotumomabPTNCI
  • Anti-P3 Antibody Idiotype Monoclonal Antibody 1E10SYNCI
  • MoAb 1E10CNNCI
  • RACOTUMOMABPTFDA52G405U1E5
DEFINITION
  • An anti-idiotype murine monoclonal antibody (MoAb) specific to P3 MoAb with anti-metastatic effect. Racotumomab binds to the idiotype region of P3 MoAb and functionally mimics the three-dimensional structure of N-glycolyl ceramides of mono-sialyl lactose, the antigenic target of P3. As a result, this anti-idiotype antibody may stimulate the host immune system to elicit humoral and cellular immune responses against tumor cells expressing NeuGc-GM3 gangliosides, which are expressed in a wide variety of tumor cells.NCI
code
  • C95024
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