About: Phagocytosis Pathway

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Attributes	Values
rdf:type	Class
rdfs:label	Phagocytosis Pathway
rdfs:subClassOf	Transport Pathway
Semantic_Type	Functional Concept
Preferred_Name	Phagocytosis Pathway
UMLS_CUI	C2984574
KEGG_ID	hsa04145
ALT_DEFINITION	Phagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is formed when the specific receptors on the phagocyte surface recognize ligands on the particle surface. After formation, nascent phagosomes progressively acquire digestive characteristics. This maturation of phagosomes involves regulated interaction with the other membrane organelles, including recycling endosomes, late endosomes and lysosomes. The fusion of phagosomes and lysosomes releases toxic products that kill most bacteria and degrade them into fragments. However, some bacteria have strategies to escape the bactericidal mechanisms associated with phagocytosis and survive within host phagocytes.KEGG
FULL_SYN	Phagocytosis PathwayPTNCI PhagosomePTKEGG
code	C91809
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