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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Sertaconazole
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Sertaconazole
UMLS_CUI
  • C0074391
CAS_Registry
  • 99592-32-2
FDA_UNII_Code
  • 72W71I16EG
Contributing_Source
  • FDA
Chemical_Formula
  • C20H15Cl3N2OS
Legacy_Concept_Name
  • Sertaconazole
FULL_SYN
  • SERTACONAZOLEPTFDA72W71I16EG
  • SertaconazolePTNCI
  • [R,S]-(+/-)-1-{2,4-Dichlor-beta-[(7-chlorbenzo[b]thien-3-yl)methoxy]phenethyl}imidazolSNNCI
DEFINITION
  • A synthetic imidazole derivative, containing a benzothiophene ring, with antifungal, antibacterial, anti-inflammatory and anti-pruritic activity. Besides its ability to inhibit the synthesis of ergosterol, the benzothiophene ring of sertaconazole is able to insert into the fungal cell wall instead of tryptophan. This increases the permeability of the cell wall. In addition, sertaconazole suppresses the release of cytokines.NCI
code
  • C75206
sameAs
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