About: Rociclovir     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Rociclovir
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Rociclovir
UMLS_CUI
  • C0643822
CAS_Registry
  • 108436-80-2
FDA_UNII_Code
  • 6DF29U51Y7
Contributing_Source
  • FDA
Chemical_Formula
  • C15H25N5O3
Legacy_Concept_Name
  • Rociclovir
FULL_SYN
  • 2-Amino-9-((2-isopropoxy-1-(isopropoxymethyl)ethoxy)methyl)purineSNNCI
  • Hoe 602CNNCI
  • ROCICLOVIRPTFDA6DF29U51Y7
  • RociclovirPTNCI
DEFINITION
  • A purine nucleoside prodrug with activity against herpes simplex virus 1. In vivo, Rociclovir is converted to ganciclovir, which is further modified to its triphosphate form and inhibits viral DNA replication by competitive inhibition of viral DNA polymerases and incorporation into viral DNA, resulting in eventual termination of viral DNA elongation.NCI
code
  • C73204
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