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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Perindopril
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Perindopril
UMLS_CUI
  • C0136123
CAS_Registry
  • 82834-16-0
FDA_UNII_Code
  • Y5GMK36KGY
Contributing_Source
  • FDA
Chemical_Formula
  • C19H32N2O5
Legacy_Concept_Name
  • Perindopril
CHEBI_ID
  • CHEBI:8024
FULL_SYN
  • PerindoprilPTNCI
  • (2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic Acid, 1-ethyl EsterSNNCI
  • S-9490CNNCI
  • PERINDOPRILPTFDAY5GMK36KGY
DEFINITION
  • A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, perindopril is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue.NCI
code
  • C72910
sameAs
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