About: Omeprazole

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Omeprazole
rdfs:subClassOf	Proton Pump Inhibitor nodeID://b697965 nodeID://b697966
Has_Salt_Form	OMEPRAZOLE MAGNESIUM Omeprazole Sodium
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Omeprazole
UMLS_CUI	C0028978
CAS_Registry	73590-58-6
FDA_UNII_Code	KG60484QX9
Contributing_Source	FDA
ALT_DEFINITION	A drug that inhibits gastric acid secretion.NCI-GLOSS
PDQ_Open_Trial_Search_ID	42309
PDQ_Closed_Trial_Search_ID	42309
Chemical_Formula	C17H19N3O3S
Legacy_Concept_Name	Omeprazole
CHEBI_ID	CHEBI:7772
FULL_SYN	omeprazolePTNCI-GLOSSCDR0000045450 OmeprazolePTDCP01015 OMEPABNCI LosecFBNCI 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazoleSNNCI H168/68CNNCI OMEPRAZOLEPTFDAKG60484QX9 PrilosecBRNCI OmeprazolePTNCI
DEFINITION	A benzimidazole with selective and irreversible proton pump inhibition activity. Omeprazole forms a stable disulfide bond with the sulfhydryl group of the hydrogen-potassium (H+ - K+) ATPase found on the secretory surface of parietal cells, thereby inhibiting the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen and suppressing gastric acid secretion. This agent exhibits no anticholinergic activities and does not antagonize histamine H2 receptors.NCI
code	C716
sameAs	OMEPRAZOLE OMEPRAZOLE
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0015293
is someValuesFrom of	nodeID://b645454 nodeID://b650549 nodeID://b660608 nodeID://b697968
is Has_Free_Acid_Or_Base_Form of	OMEPRAZOLE MAGNESIUM Omeprazole Sodium
is sameAs of	OMEPRAZOLE OMEPRAZOLE OMEPRAZOLE OMEPRAZOLE

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