About: Angiotensin II Receptor Antagonist     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Angiotensin II Receptor Antagonist
rdfs:subClassOf
Semantic_Type
  • Chemical Viewed Functionally
Preferred_Name
  • Angiotensin II Receptor Antagonist
UMLS_CUI
  • C0521942
Legacy_Concept_Name
  • Angiotensin_II_Receptor_Antagonist
FULL_SYN
  • Angiotensin II Receptor AntagonistPTNCI
  • Angiotensin II Receptor AntagonistsSYNCI
  • ARBABNCI
  • Angiotensin Receptor BlockersSYNCI
  • Angiotensin II Receptor BlockerSYNCI
DEFINITION
  • A class of agents that act by selectively inhibiting angiotensin II receptor activation in the renin-angiotensin-aldosterone system. Angiotensin II receptor antagonists bind to and block the activation of angiotensin II type 1 (AT1) receptors, thereby reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. Although this class of agents is also used in diabetic nephropathy (kidney damage due to diabetes) and congestive heart failure, it is primarily used for the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy.NCI
code
  • C66930
is rdfs:subClassOf of
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