About: Zofenoprilat Arginine     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Zofenoprilat Arginine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Zofenoprilat Arginine
UMLS_CUI
  • C0646135
CAS_Registry
  • 81872-09-5
FDA_UNII_Code
  • 36F26ZSQ0D
Contributing_Source
  • FDA
Chemical_Formula
  • C15H19NO3S2.C6H14N4O2
Legacy_Concept_Name
  • Zofenoprilat_Arginine
FULL_SYN
  • ZOFENOPRILAT ARGININEPTFDA36F26ZSQ0D
  • SQ 26703CNNCI
  • L-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-4-(phenylthio)-, (1(R*),2alpha,4alpha)-, compd. with L-arginine (1:1)SNNCI
  • SQ 26,703CNNCI
  • Zofenoprilat ArgininePTNCI
DEFINITION
  • The arginine salt of zofenoprilat, a sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Zofenoprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Zofenoprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.NCI
code
  • C66700
http://linked.open...y/mesh/hasConcept
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 46 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software