About: Temarotene     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Temarotene
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Temarotene
UMLS_CUI
  • C0076076
CAS_Registry
  • 75078-91-0
FDA_UNII_Code
  • A28G39IJ7K
Contributing_Source
  • FDA
Chemical_Formula
  • C23H28
Legacy_Concept_Name
  • Temarotene
FULL_SYN
  • TemarotenePTDCP30569
  • 1,2,3,4-Tetrahydro-1,1,4,4-tetramethyl-6-[(1E)-1-methyl-2-phenylethenyl]naphthaleneSNNCI
  • TTNPB, Decarboxylated AnalogSYNCI
  • TEMAROTENEPTFDAA28G39IJ7K
  • TemarotenSYNCI
  • Ro 15-0778CNNCI
  • TemarotenePTNCI
DEFINITION
  • A synthetic bioactive retinoid with differentiation inducing and potential antineoplastic activities. Like other retinoic acid agents, temarotene binds to and activates retinoic acid receptors (RARs), thereby altering the expression of certain genes leading to cell differentiation and decreased cell proliferation in susceptible cells.NCI
code
  • C63953
http://linked.open...y/mesh/hasConcept
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