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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Naloxone
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Naloxone
UMLS_CUI
  • C0027358
CAS_Registry
  • 465-65-6
FDA_UNII_Code
  • 36B82AMQ7N
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is being studied as a treatment for constipation caused by narcotic medications. It belongs to the family of drugs called narcotic antagonists.NCI-GLOSS
Chemical_Formula
  • C19H21NO4
Legacy_Concept_Name
  • Naloxone_Base
CHEBI_ID
  • CHEBI:7459
FULL_SYN
  • (-)-NaloxoneSYDTPNSC0070413
  • NALOXONEPTFDA36B82AMQ7N
  • NaloxoneSYDTPNSC0070413
  • naloxonePTNCI-GLOSSCDR0000045228
  • NaloxonePTNCI
  • NaloxonePTDCP30318
DEFINITION
  • A thebaine derivate with competitive opioid antagonistic properties. Naloxone reverses the effects of opioid analgesics by binding to the opioid receptors in the CNS, and inhibiting the typical actions of opioid analgesics, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence. Naloxone binds to mu-opioid receptors with a high affinity, and a lesser degree to kappa- and gamma-opioid receptors in the CNS.NCI
code
  • C62054
sameAs
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