About: Fosamprenavir Calcium     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Fosamprenavir Calcium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Fosamprenavir Calcium
UMLS_CUI
  • C1320129
CAS_Registry
  • 226700-81-8
FDA_UNII_Code
  • ID1GU2627N
Contributing_Source
  • FDA
Chemical_Formula
  • C25H34N3O9PS.Ca
Legacy_Concept_Name
  • Fosamprenavir_Calcium
FULL_SYN
  • FOSAMPRENAVIR CALCIUMPTFDAID1GU2627N
  • 908SYNCI
  • LexivaBRNCI
  • GW433908SYNCI
  • Fosamprenavir CalciumPTNCI
DEFINITION
  • The calcium salt form of fosamprenavir, prodrug of amprenavir, and a human immunodeficiency virus (HIV) protease inhibitor with antiviral property. Fosamprenavir is converted to amprenavir by cellular phosphatases in the epithelial cells of the intestine. Then amprenavir binds to the active site of HIV-1 protease, thereby preventing the proteolytic cleavage of viral Gag-Pol polypeptide into individual functional proteins, thereby leading to the formation of immature non-infectious viral particles.NCI
code
  • C61771
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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