About: G250 Peptide Vaccine     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • G250 Peptide Vaccine
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • G250 Peptide Vaccine
UMLS_CUI
  • C1711251
PDQ_Open_Trial_Search_ID
  • 465193
PDQ_Closed_Trial_Search_ID
  • 465193
Legacy_Concept_Name
  • G250_Peptide_Vaccine
FULL_SYN
  • G250 Peptide VaccinePTNCI
DEFINITION
  • A cancer vaccine containing of a synthetic form of the renal cell carcinoma (RCC)-associated antigen G250 with potential antineoplastic activity. Vaccination with G250 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the G250 antigen, resulting in decreased tumor growth. Found in the majority of renal cell carcinomas, G250 is a cell surface tumor-associated antigen (TAA) that contains an HLA-A2.1-restricted epitope that is recognized by CTLs.NCI
code
  • C53410
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