About: Yttrium Y-90 Tacatuzumab Tetraxetan     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Yttrium Y-90 Tacatuzumab Tetraxetan
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Yttrium Y-90 Tacatuzumab Tetraxetan
UMLS_CUI
  • C1541525
CAS_Registry
  • 476413-07-7
FDA_UNII_Code
  • GJ2416WK6Y
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance being studied in the treatment of liver cancer. HuAFP31 is a monoclonal antibody that can bind to tumor cells that make a protein called alpha fetoprotein (AFP). It is linked to a radioactive substance called yttrium Y 90, which may help kill the cancer cells. Yttrium Y 90 DOTA monoclonal antibody HuAFP31 is a type of radioimmunoconjugate.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 425347
PDQ_Closed_Trial_Search_ID
  • 425347
Chemical_Formula
  • C16H25N5O7.Y
Legacy_Concept_Name
  • Yttrium_Y_90_DOTA_Monoclonal_Antibody_HuAFP31
FULL_SYN
  • Y-90 hAFP-31ABNCI
  • yttrium Y 90 DOTA monoclonal antibody HuAFP31PTNCI-GLOSSCDR0000560639
  • Yttrium Y 90 DOTA Monoclonal Antibody HuAFP31SYNCI
  • Yttrium Y 90 Tacatuzumab TetraxetanSYNCI
  • Yttrium Y-90 Tacatuzumab TetraxetanPTNCI
  • Yttrium Y-90 Tacatuzumab TetraxetanSYNCI
  • AFP-CideBRNCI
  • YTTRIUM Y-90 TACATUZUMAB TETRAXETANPTFDAGJ2416WK6Y
DEFINITION
  • A radioimmunoconjugate comprised of the humanized monoclonal antibody tacatuzumab, directed against alpha fetoprotein, that is conjugated to the chelating agent tetraxetan and radiolabeled with the beta-emitting radioisotope Yttrium Y 90. Yttrium Y 90 tacatuzumab tetraxetan binds to tumor cells expressing alpha fetoprotein, thereby selectively delivering a cytotoxic dose of beta radiation.NCI
code
  • C48428
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