About: Tirofiban Hydrochloride     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tirofiban Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Tirofiban Hydrochloride
UMLS_CUI
  • C0795668
CAS_Registry
  • 150915-40-5
FDA_UNII_Code
  • 6H925F8O5J
Contributing_Source
  • FDA
Chemical_Formula
  • C22H36N2O5S.HCl.H2O
Legacy_Concept_Name
  • Tirofiban_Hydrochloride
CHEBI_ID
  • CHEBI:9606
FULL_SYN
  • Tirofiban HydrochloridePTNCI
  • Tirofiban Hydrochloride MonohydrateSYNCI
  • TIROFIBAN HYDROCHLORIDEPTFDA6H925F8O5J
  • N-(Butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-L-tyrosine MonohydrochlorideSNNCI
  • MK 383CNNCI
  • AggrastatBRNCI
DEFINITION
  • The hydrochloride salt form of tirofiban, a non-peptide tyrosine derivative with anticoagulant property. Tirofiban antagonizes fibrinogen binding to the platelet cell surface receptor, glycoprotein (GP) IIb/IIIA complex, one of the two purinergic receptors activated by ADP. The antagonism prevents adenylyl cyclase activation, which mediated via GP IIb/IIIa receptor complex, and results in decreased levels of cAMP and thereby interferes with platelet membrane function and subsequent platelet-platelet interaction, release of platelet granule constituents and prolongation of bleeding time.NCI
code
  • C47759
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 46 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software