About: Quinupristin     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Quinupristin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Quinupristin
UMLS_CUI
  • C0756081
CAS_Registry
  • 120138-50-3
FDA_UNII_Code
  • 23OW28RS7P
Contributing_Source
  • FDA
Chemical_Formula
  • C53H67N9O10S
Legacy_Concept_Name
  • Quinupristin
FULL_SYN
  • QUINUPRISTINPTFDA23OW28RS7P
  • QuinupristinPTNCI
  • N-((6R,9S,10R,13S,15aS,18R,22S,24aS)-22-(p-(Dimethylamino)benzyl)-6-ethyldocosahydro-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyl-18-(((3S)-3-quinuclidinylthio)methyl)-12H-pyrido(2,1-f)pyrrolo(2,1-l)(1,4,7,10,13,16)oxapentaazacyclononadecin-9-yl)-3-hydroxypicolinamideSNNCI
  • Virginiamycin S1, 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic Acid)-,(S)-SNNCI
DEFINITION
  • A semi-synthetic derivative of pristinamycin, a natural occurring type B streptogramin. Quinupristin binds to the bacterial 50S ribosomal subunit, thereby inhibiting peptide chain elongation, and causing early termination of normal bacterial protein synthesis. Quinupristin is primarily effective against gram-positive cocci.NCI
code
  • C47701
sameAs
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