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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Flumazenil
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Flumazenil
UMLS_CUI
  • C0016293
CAS_Registry
  • 78755-81-4
FDA_UNII_Code
  • 40P7XK9392
Contributing_Source
  • FDA
Chemical_Formula
  • C15H14FN3O3
Legacy_Concept_Name
  • Flumazenil
CHEBI_ID
  • CHEBI:5103
FULL_SYN
  • 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic Acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo-, Ethyl EsterSNNCI
  • AnexateSYNCI
  • LanexatSYNCI
  • FLUMAZENILPTFDA40P7XK9392
  • Ro 151788CNNCI
  • RomaziconBRNCI
  • FlumazenilPTNCI
DEFINITION
  • An imidazo-benzodiazepine derivative, effective in reversing benzodiazepine-induced activities. Flumazenil antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel opening events and inhibiting neuronal hyperpolarization. As a result, flumazenil reverses benzodiazepine-induced effects including sedation, psychomotor deficits, amnesia, and hypoventilation in a dose-dependent manner.NCI
code
  • C47534
sameAs
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