About: Ergotamine Tartrate     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Ergotamine Tartrate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ergotamine Tartrate
NSC_Code
  • 41869
UMLS_CUI
  • C2936189
CAS_Registry
  • 24381-56-4
  • 379-79-3
FDA_UNII_Code
  • MRU5XH3B48
Contributing_Source
  • FDA
Chemical_Formula
  • 2C33H35N5O5.C4H6O6
Legacy_Concept_Name
  • Ergotamine_Tartrate
FULL_SYN
  • ErgomarBRNCI
  • LingranSYNCI
  • SecupanSYNCI
  • Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-,(5'alpha)-,(2R,3R)-2,3-dihydroxybutanedioate(2:1)(salt)SNNCI
  • Ergotamine TartratePTNCI
  • FemerginSYNCI
  • ErgostatSYNCI
  • ERGOTAMINE TARTRATEPTFDAMRU5XH3B48
  • WigrettesBRNCI
DEFINITION
  • The tartrate salt form of ergotamine, an ergot alkaloid and adrenergic alpha agonist with vasoconstrictor activity. Ergotamine tartrate selectively binds to alpha-adrenergic receptors thereby stimulating vascular smooth muscle and causing vasoconstriction in both arteries and veins. Ergotamine tartrate also blocks serotonin 5-HT1D receptors, thereby also causing vasoconstriction in cerebral blood vessels. Constriction of cerebral blood vessels caused by this agent may reduce the blood flow and pressure in cerebral arteries and may relieve the pain of vascular headaches.NCI
code
  • C47517
sameAs
is Has_Salt_Form of
is sameAs of
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