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AttributesValues
rdf:type
rdfs:label
  • Bivalirudin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Bivalirudin
UMLS_CUI
  • C0168273
CAS_Registry
  • 128270-60-0
FDA_UNII_Code
  • TN9BEX005G
Contributing_Source
  • FDA
Chemical_Formula
  • C98H138N24O33
Legacy_Concept_Name
  • Bivalirudin
CHEBI_ID
  • CHEBI:59173
FULL_SYN
  • BivalirudinPTNCI
  • BivalirudinSYNCI
  • HirulogSYNCI
  • AngiomaxBRNCI
  • L-Leucine, D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-SNNCI
  • BIVALIRUDINPTFDATN9BEX005G
DEFINITION
  • A 20 amino acid long synthetic peptide with thrombin-specific anticoagulant properties. Bivalirudin reversibly binds thrombin, free as well as clot bound, at the catalytic site and the anion-binding exosite, thereby preventing the formation and activation of fibrin, factor XIIIa, and other coagulation factors. This drug is primarily used during coronary angioplasty procedures, in combination with aspirin, in patients with unstable angina.NCI
code
  • C47415
sameAs
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