About: Histone Deacetylation

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Histone Deacetylation
rdfs:subClassOf	Post-Translational Modification
Semantic_Type	Physiologic Function
Preferred_Name	Histone Deacetylation
UMLS_CUI	C1156201
Legacy_Concept_Name	Histone_Deacetylation
FULL_SYN	Histone DeacetylationPTNCI
DEFINITION	Histone Deacetylation is the covalent post-translational enzymatic addition of an acetyl group(s) to a histone protein. By exposing cationic sites on the protein that promote ionic interaction with the negatively charged DNA backbone, Histone Deacetylation induces DNA condensation and regulates genetic functions, such as transcription. (NCI)NCI
code	C40580
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