About: Sumoylation Regulation of Transcriptional Repression Pathway

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Attributes	Values
rdf:type	Class
rdfs:label	Sumoylation Regulation of Transcriptional Repression Pathway
rdfs:subClassOf	Regulatory Pathway
Semantic_Type	Functional Concept
Preferred_Name	Sumoylation Regulation of Transcriptional Repression Pathway
UMLS_CUI	C1515053
BioCarta_ID	h_ranbp2Pathway
ALT_DEFINITION	Current data indicates that nuclear pore complex (NPC) RanBP2 (SUMO E3 ligase) protein sumoylates Mdm2 and HDAC proteins during nuclear translocation. A sumoylation-deficient HDAC showed reduced deacetylation activity and suggests that sumoylation may be an important regulatory mechanism for the control of transcriptional repression.BIOCARTA
Legacy_Concept_Name	Sumoylation_Regulation_of_Transcriptional_Repression_Pathway
FULL_SYN	Sumoylation Regulation of Transcriptional Repression PathwayPTNCI Sumoylation by RanBP2 Regulates Transcriptional RepressionPTBIOCARTA
code	C39211
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