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AttributesValues
rdf:type
rdfs:label
  • Chlorambucil
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Chlorambucil
NSC_Code
  • 3088
UMLS_CUI
  • C0008163
CAS_Registry
  • 305-03-3
Accepted_Therapeutic_Use_For
  • chronic lymphocytic leukemia, Hodgkin lymphoma, and certain types of non-Hodgkin lymphoma.
In_Clinical_Trial_For
  • Chronic lymphocytic leukemia; Follicular lymphoma; Hodgkins lymphoma
FDA_UNII_Code
  • 18D0SL7309
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat several types of leukemias and lymphomas. It blocks cell growth by damaging the cell's DNA and may kill cancer cells. It is a type of alkylating agent.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 43113
PDQ_Closed_Trial_Search_ID
  • 43113
Chemical_Formula
  • C14H19Cl2NO2
Legacy_Concept_Name
  • Chlorambucil
CHEBI_ID
  • CHEBI:28830
FULL_SYN
  • AmbochlorinSYDTPNSC0003088
  • p-N, N-di-(beta-chloroethyl)aminophenyl butyric acidSNNCI
  • ChlorbutineSYDTPNSC0003088
  • ChlorobutinSYDTPNSC0003088
  • N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acidSNNCI
  • AmbochlorinBRNCI
  • ChlorbutineSYNCI
  • ChlorobutinSYNCI
  • LympholysinSYNCI
  • .gamma.-(p-bis(2-chloroethyl)aminophenyl)butyric acidSYDTPNSC0003088
  • ChlorambucilSYDTPNSC0003088
  • ChlorobutineSYDTPNSC0003088
  • .gamma.-[p-bis(2-chloroethyl)aminophenyl]butyric acidSYDTPNSC0003088
  • ChlorambucilPTNCI
  • ChlorobutineSYNCI
  • p-N, N-Di-(.beta.-chloroethyl)aminophenyl butyric acidSYDTPNSC0003088
  • chlorbutinumSYNCI
  • 4-[Bis(2-chloroethyl)amino]benzenebutanoic acidSYDTPNSC0003088
  • N,N-di-2-chloroethyl-.gamma.-p-aminophenylbutyric acidSNNCI
  • N,N-Di-2-chloroethyl-.gamma.-p-aminophenylbutyric acidSYDTPNSC0003088
  • chloroambucilSYNCI
  • ChloroambucilSYDTPNSC0003088
  • CB 1348SYDTPNSC0003088
  • phenylbutyric acid nitrogen mustardSYNCI
  • ChlorambucilumSYNCI
  • ChloraminophenSYNCI
  • CHLABNCI
  • chlorambucilPTNCI-GLOSSCDR0000046048
  • p-(N, N-Di-2-chloroethyl)aminophenyl butyric acidSYDTPNSC0003088
  • ChloraminophenSYDTPNSC0003088
  • benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]- (9CI)SNNCI
  • ChloraminopheneFBNCI
  • Phenylbutyric acid nitrogen mustardSYDTPNSC0003088
  • EclorilSYDTPNSC0003088
  • ElcorilSYDTPNSC0003088
  • Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]- (9CI)SYDTPNSC0003088
  • 4-[p-[Bis(2-chloroethyl)amino]phenyl]butyric acidSYDTPNSC0003088
  • 4-[bis(2-chloroethyl)amino]benzenebutanoic acidSNNCI
  • Butyric acid, 4-(p-bis(2-chloroethyl)aminophenyl)-SYDTPNSC0003088
  • ChloraminopheneSYDTPNSC0003088
  • LeukoranSYDTPNSC0003088
  • Alti-chlorambucilFBNCI
  • aminochlorambucilSYNCI
  • p-(N, N-di-2-chloroethyl)aminophenyl butyric acidSNNCI
  • CB-1348CNNCI
  • butyric acid, 4-(p-bis(2-chloroethyl)aminophenyl)SNNCI
  • 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acidSNNCI
  • EclorilSYNCI
  • ElcorilSYNCI
  • LeukersanSYDTPNSC0003088
  • LeukeranPTNCI-GLOSSCDR0000662514
  • LeukeranBRNCI
  • LeukoranSYNCI
  • WR-139013CNNCI
  • AminochlorambucilSYDTPNSC0260461
  • gamma-[p-di(2-chloroethyl)aminophenyl]butyric acidSNNCI
  • Butyric acid, 4-(p-[bis(2-chloroethyl)amino]phenyl)-SYDTPNSC0003088
  • AmboclorinSYDTPNSC0003088
  • ChlorbutinSYDTPNSC0003088
  • LinfolizinSYDTPNSC0003088
  • LinfolysinSYDTPNSC0003088
  • LeukersanSYNCI
  • gamma-(p-bis(2-chloroethyl)aminophenyl)butyric acidSNNCI
  • .gamma.-[p-Di(2-chloroethyl)aminophenyl]butyric acidSYDTPNSC0003088
  • AmboclorinBRNCI
  • LinfolizinBRNCI
  • ChlorbutinSYNCI
  • LinfolysinFBNCI
  • LinfolizinSYNCI
  • CHLORAMBUCILPTFDA18D0SL7309
DEFINITION
  • An orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. (NCI04)NCI
code
  • C362
sameAs
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