About: CA-125 Antigen     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • CA-125 Antigen
rdfs:subClassOf
Semantic_Type
  • Carbohydrate
  • Immunologic Factor
Preferred_Name
  • CA-125 Antigen
UMLS_CUI
  • C0006610
Accepted_Therapeutic_Use_For
  • Monitoring levels in patients with Ovarian Cancer
In_Clinical_Trial_For
  • Ovarian epithelial; peritoneal; fallopian tube cancer
ALT_DEFINITION
  • A substance that may be found in high amounts in the blood of patients with certain types of cancer, including ovarian cancer. CA-125 levels may also help monitor how well cancer treatments are working or if cancer has come back.NCI-GLOSS
Legacy_Concept_Name
  • CA-125_Antigen
FULL_SYN
  • cancer antigen 125PTNCI-GLOSSCDR0000579637
  • Carbohydrate Antigen 125SYNCI
  • CA-125 AntigenPTNCI
  • CA-125PTNCI-GLOSSCDR0000046490
  • CA-125 AntigenSYNCITCGA
  • CA125SYNCI
  • CA-125SYNCI
  • Cancer Antigen 125SYNCI
DEFINITION
  • An antigen expressed by tissues derived from mullerian epithelium (tubal, endometrial and endocervical) or celomic epithelium (mesothelial cells of the pleura, pericardium and peritoneum). Although its biochemical nature has not been clearly defined, CA125 has been described as a glycosylated, high-molecular-weight protein that may be released from damaged cells. Measurable in plasma, CA125 is a sensitive, nonspecific tumor marker for ovarian cancer; as such it is much more useful for monitoring clinical responses to the treatment of ovarian cancer than for the diagnosis of ovarian cancer. Elevated plasma CA125 may occur in association with other malignancies and non-malignant gynecologic disorders. (NCI04)NCI
code
  • C325
sameAs
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