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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Emofolin Sodium
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Emofolin Sodium
NSC_Code
  • 139490
UMLS_CUI
  • C0098575
CAS_Registry
  • 52386-42-2
Legacy_Concept_Name
  • Emfolin_Sodium
FULL_SYN
  • MeTHHF DisodiumABNCI
  • Emofolin SodiumPTNCI
  • MethyltetrahydrohomofolateSYNCI
DEFINITION
  • The sodium salt of a synthetic antimetabolite analogue of folate with antineoplastic activity. Emfolin sodium competes for the folate binding site of the enzyme dihydrofolate reductase, resulting in inhibition of tetrahydrofolate synthesis, depletion of nucleotide pools, and inhibition of DNA, RNA and protein synthesis. (NCI04)NCI
code
  • C29019
http://linked.open...y/mesh/hasConcept
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