About: Cytochrome P450 2C9     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Cytochrome P450 2C9
equivalentClass
OMIM_Number
  • 601130
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
Preferred_Name
  • Cytochrome P450 2C9
UMLS_CUI
  • C0608437
Legacy_Concept_Name
  • Cytochrome-P450-2C9
FULL_SYN
  • Flavoprotein-Linked MonooxygenaseSYNCI
  • Microsomal MonooxygenaseSYNCI
  • Cytochrome P450, Family 2, Subfamily C, Polypeptide 9SYNCI
  • EC 1.14.13.-SYNCI
  • EC 1.14.13.80SYNCI
  • EC 1.14.13.48SYNCI
  • EC 1.14.13.49SYNCI
  • Xenobiotic MonooxygenaseSYNCI
  • Mephenytoin 4-HydroxylaseSYNCI
  • Cytochrome P450, Subfamily IIC (Mephenytoin 4-Hydroxylase), Polypeptide 9SYNCI
  • Cytochrome P450, Subfamily IIC (Mephenytoin 4-Hydroxylase), Polypeptide 10SYNCI
  • S-Mephenytoin 4-HydroxylaseSYNCI
  • (R)-Limonene 6-MonooxygenaseSYNCI
  • (S)-Limonene 7-MonooxygenaseSYNCI
  • CYP2C9SYNCI
  • Cytochrome P-450MPSYNCI
  • P-450MPSYNCI
  • CYPIIC9SYNCI
  • Cytochrome P450 2C9PTNCI
  • Cytochrome P450 PB-1SYNCI
  • Cytochrome P450 MP-4SYNCI
  • Cytochrome P450 MP-8SYNCI
  • P450 PB-1SYNCI
  • P450 MP-4SYNCI
Swiss_Prot
  • P11712
DEFINITION
  • Cytochrome P450 2C9 (490 aa, ~56 kDa) is encoded by the human CYP2C9 gene. This protein is involved in the oxidation of fatty acids, steroids and xenobiotics.NCI
DesignNote
  • Cytochrome P450 2C9 contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan. (UniProt)
code
  • C28750
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