About: Proteinase 3:PR1 Peptide     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:DeprecatedClass, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Proteinase 3:PR1 Peptide
rdfs:subClassOf
Has_Target
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Proteinase 3:PR1 Peptide
OLD_KIND
  • Chemicals_and_Drugs_Kind
Concept_Status
  • Retired_Concept
FULL_SYN
  • Proteinase 3:PR1 PeptidePTNCI
DEFINITION
  • A synthetic HLA-A2-restricted nonapeptide derived from proteinase 3 with potential use in cancer immunotherapy. Cytotoxic T lymphocytes (CTL) primed with proteinase 3 PR1 peptide attack leukemic cells that express proteinase 3 aberrantly. Proteinase 3 is a serine proteinase that activates progelatinase A and is involved in metastasis and angiogenesis. (NCI04)NCI
DesignNote
  • See 'PR1 Leukemia Peptide Vaccine'
code
  • C2797
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