About: Homeobox Protein Hox-A9     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Homeobox Protein Hox-A9
equivalentClass
OMIM_Number
  • 142956
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Biologically Active Substance
Preferred_Name
  • Homeobox Protein Hox-A9
UMLS_CUI
  • C0386322
Legacy_Concept_Name
  • Homeobox_Protein-A9
FULL_SYN
  • Homeobox Protein HOXA9SYNCI
  • Homeobox Protein Hox-1GSYNCI
  • Homeobox Protein Hox-A9PTNCI
  • HOXA9 ProteinSYNCI
  • Homeodomain Protein HOXA9SYNCI
  • ABD-BSYNCI
  • HOX1GSYNCI
  • HOXA9SYNCI
  • HOX1.7SYNCI
  • Hox-1GSYNCI
  • Homeobox Protein 1GSYNCI
  • Homeobox Protein A9SYNCI
Swiss_Prot
  • P31269
DEFINITION
  • Homeobox protein Hox-A9 (272 aa, ~30 kDa) is encoded by the human HOXA9 gene. This protein is involved in transcriptional regulation that drives embryonic development.NCI
DesignNote
  • Homeobox Protein A9 isoforms are class I sequence-specific DNA-binding homeobox transcription factors potentially involved in morphogenesis and myeloid differentiation; expression is spatially and temporally regulated during embryonic development. Frameshifted isoform B contains a distinct C-terminus lacking the homeodomain. HOXA9 acts within a developmental regulatory system that provides specific anterior-posterior positional identity to cells. Associated with acute myeloid leukemogenesis, a chimerically fused in-frame nucleoporin NUP98 amino terminal half to HOXA9 may inhibit differentiation or disrupt nucleocytoplasmic transport. (from LocusLink, Swiss-Prot, OMIM)
code
  • C26310
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