About: I 131 Antiferritin Immunoglobulin     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • I 131 Antiferritin Immunoglobulin
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • I 131 Antiferritin Immunoglobulin
UMLS_CUI
  • C0280029
In_Clinical_Trial_For
  • non-metastatic non-resectable primary hepatoma.
PDQ_Open_Trial_Search_ID
  • 40362
PDQ_Closed_Trial_Search_ID
  • 40362
Legacy_Concept_Name
  • I_131_Antiferritin_Immunoglobulin
FULL_SYN
  • I 131-antiferritin IgGSYNCI
  • I 131 Antiferritin ImmunoglobulinPTNCI
  • Iodine I 131 Antiferritin ImmunoglobulinSYNCI
  • I 131-AFIABNCI
  • immunoglobulin, iodine I 131 antiferritinSYNCI
DEFINITION
  • A radioimmunoconjugate of a rabbit antihuman ferritin IgG labeled with iodine 131 (I-131). Using anti-ferritin IgG as a carrier for I-131 may result in the targeted imaging and/or destruction of cells expressing ferritin. Observed in 35% to 100% of patients with hepatocellular carcinoma, high serum ferritin levels may be due to ferritin production by the tumor cells, or related to the associated iron overload and/or cirrhosis.NCI
code
  • C2357
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